The Centre for Health Protection has learned of two avian influenza A (H7N9) cases in Hunan, involving two men.
One of them, aged 57, had been exposed to poultry and is in critical condition.
The other, a 75-year-old patient, has died.
The centre reminded travellers to the Mainland and other avian influenza-affected areas not to visit live poultry markets and farms, and to avoid contact with poultry and their droppings.